Helping detect early disease patterns with whole-body MRI
Powered by the world’s largest internal whole-body MRI database, the Prenuvo Research Network brings together leading researchers and academics to help advance early detection efforts and human health biomarker science.
Shifting the healthcare paradigm from reactive to proactive.
The Prenuvo Research Network is a collaboration of researchers, physicians, and academic institutions working together to study how whole-body MRI can help detect certain conditions earlier than conventional tools may allow.
We provide collaborators with access to the world's largest internal clinical whole-body MRI dataset—and the infrastructure to turn it into publishable science. All studies follow applicable ethical, patient safety, data integrity and regulatory compliance requirements, including collaborator institution IRB review where required.
Data points collected per scan, across imaging and biomarker data.
Personalized health insights across its member base.
Universities and research institutions collaborating worldwide.
Whole-body MRI scans powering the world’s largest internal de-identified dataset for clinical research.
Prospectively enrolled participants to date in our longitudinal observational Hercules-study cohort.
Peer-reviewed scientific publications and academic abstracts.
Large-scale, real-world, observational research
Hercules
A prospective observational study aiming to enroll up to 100,000 participants to evaluate how whole-body MRI screening can help predict clinically significant diagnoses (CSD) in the general population and explore new biomarkers of disease.
Target participants
Trial in Progress abstract presented in 2025
Study design
Polaris
A retrospective observational study of 1,011 participants examining the baseline cancer detection rates of elective whole-body MRI screening in an asymptomatic population, helping establish early milestones for hidden solid tumors and silent conditions.*
Participants
Presented at
Study design
*The outcomes of Prenuvo’s internal Polaris Study were based, in part, on patient-reported data and may be subject to responder bias. Findings should be interpreted in the context of these study limitations and have not yet been independently replicated.
Evidence worth exploring
Peer-reviewed research, real-world clinical case studies, and in-depth white papers on the power of whole-body MRI—a window into what proactive screening can help reveal.
Research articles
Visceral Abdominal Fat Predicts Brain Atrophy at Midlife in 10,001 Individuals
A deep-learning analysis linking AI-quantified visceral fat to brain volume across a 10,001-person cohort.
White papers
Beyond Cancer: WB-MRI as a Platform for Multi-Organ Preventative Screening
Whole-body MRI expands beyond cancer detection to enable radiation-free, multi-organ prevention, risk stratification, and proactive longitudinal whole-body health monitoring.
Building an unprecedented picture of how disease develops over time
01
Uniting expertise across 50+ institutions
Our initial collaborators represent experts including those from City of Hope, UCSF, and Moffitt Cancer Center—examining real-world medical questions in ways constrained academic research cannot.
02
Studying early signs of structural & physiological change in the human body
Using the Prenuvo Imaging Biobank, we investigate how organs may change before symptoms appear—enabling research into Alzheimer’s, spinal aging, and other non-communicable diseases beyond conventional guidelines.
03
Generating meaningful insights into chronic diseases
Early findings show meaningful insights into a range of conditions—producing peer-reviewed research across many cancers, brain health, metabolic disease, and cardiovascular risk.
Research and Medical Affairs Team
